Dehydration (which results in tremors, weakness, fainting, blurred vision, and kidney damage), low blood pressure, a rapid heartbeat, postural dizziness, and fainting are some of the less severe side effects of laxative abuse; however, it can also result in potentially fatal acid-base and electrolyte imbalances. For instance, Laxatives misuse has been linked to distal renal tubular acidosis and severe hypokalaemia. The most frequent acid-base imbalance seen is metabolic alkalosis. Rhabdomyolysis, steatorrhoea, colonic mucosal inflammation and ulceration, pancreatitis, kidney failure, factitious diarrhoea, and other issues are among the serious side effects. A lazy colon, infections, irritable bowel syndrome, and probable liver damage will ensue from the colon's increased demand for laxatives to maintain function.
Although some people who suffer from eating disorders like anorexia and bulimia nervosa abuse laxatives in an effort to lose weight, laxatives only hasten the transit of faeces through the large intestine, which happens after the absorption of nutrients in the small intestine is finished. As a result, investigations on the misuse of laxatives have discovered that effects on body weight mostly reflect transient losses of body water rather than loss of energy (calories).
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