Radiation therapy doesn't hurt when used alone. Several low-dose palliative therapies, including Radiotherapy for skeletal metastases, have few to no adverse effects, but oedema that presses on the nerves in the treated area might produce a brief pain flare-up in the days after treatment. In the months or years following therapy (long-term side effects), after re-treatment, or both, higher doses might result in a variety of side effects (cumulative side effects). The radiation treatment itself (radiation type, dose, fractionation, concomitant chemotherapy) and the patient have an impact on the kind, severity, and longevity of side effects.
Most adverse consequences are foreseeable and anticipated. Radiation side effects often only affect the part of the patient's body that is being treated. For instance, higher doses of head and neck radiation may be linked to cardiovascular issues, thyroid dysfunction, and pituitary axis dysfunction. Side effects are dose-dependent. Contemporary Radiotherapy tries to minimise adverse effects and assist patients in understanding and coping with those that are unavoidable.
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