Metabolomics has risen quickly in the last decade, owing to developments in instrumentation and significant investment in laboratories with competence in this area of analytical chemistry. Metabolomics provides a window into cellular metabolism by adding biochemical evidence to other technologies such as genomes and proteomics. The primary difficulty in metabolomics is that it is presently not possible to detect and quantify the full metabolome using a single analytical approach.
Mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy are the primary Metabolomics Services. Because of its high sensitivity, mass spectrometry can detect metabolites in extremely low concentrations. NMR spectroscopy is nondestructive and quantitatively reproducible. Modern NMR techniques are useful instruments for elucidating the structures of unknown substances and enabling in vivo research. Mass spectrometry and nuclear magnetic resonance (NMR) are both effective technologies for isotope tracing studies that allow scientists to assess metabolite dynamics.
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