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Many patients with Lyme disease have persistent symptoms such exhaustion, cognitive problems, and musculoskeletal discomfort, which have been recognized in clinical practice for many years.
Many patients with Lyme disease have persistent symptoms such exhaustion, cognitive problems, and musculoskeletal discomfort, which have been recognized in clinical practice for many years. Prospective and population-based studies in Lyme disease-endemic areas have both shown moderate to severe symptoms that have been described in the literature. Several illness-causing mechanisms have been postulated, including microbial persistence, host immunological dysregulation via inflammatory or secondary autoimmune pathways, or altered brain networks, such as central sensitization, as the cause of these symptoms. https://re-origin.com/conditions/chronic-lyme-disease/